Method - permGWAS - a permutation-based LMM method to compute adjusted significance thresholds in GWAS
Scientific field
Natural science -
Biology -
Genetics -
GWAS
Description
permGWAS is open-source, publicly available tool for the permutation-based determination of genotype-phenotype relationships while accounting for population structure and cryptic relatedness. Links to the manuscript and GitHub can be found in the links section. Citation: Maura John, Markus J Ankenbrand, Carolin Artmann, Jan A Freudenthal, Arthur Korte, Dominik G Grimm, Efficient permutation-based genome-wide association studies for normal and skewed phenotypic distributions, Bioinformatics, Volume 38, Issue Supplement_2, September 2022, Pages ii5ii12, https://doi.org/10.1093/bioinformatics/btac455
This method was created on 20 Oct 22
by team TransBio